The complement system (C) is a critical arm of innate immunity and links both, innate and adaptive immunity. It is the first line of defense and protects the host by recognizing and eliminating ...

Activation of the complement system through the alternative pathway is necessary for the development of anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) in animal models C5a has ...

Neuroinflammation is associated with a wide spectrum of acute and chronic diseases of the central and peripheral nervous system. It causes secondary damage, which is a major determinant for ...

The complement system plays an important role in the etiology of many autoimmune diseases, including cold agglutinin disease (CAD), a subset of autoimmune hemolytic anemia. In CAD, auto-antibodies ...

Long Covid patients face ongoing issues like tiredness and difficulty breathing. Researchers from the University of Zurich and University Hospital Zurich found that the complement system, a part of ...

The complement system is a part of the immune system that enhances (complements) the ability of antibodies and phagocytic cells to clear microbes and damaged cells from an organism, promotes ...