Genome sequencing has transformed biomedical research, but it is only the first step toward understanding biological systems. Subsequent steps include the determination of three-dimensional (3D) ...

Figure 1: Distribution of the % sequence identity between the known protein structures and proteins of Mycobaterium genitalium, modeled as in ref. 13 in February, 2000. The targets for structure ...

TORONTO--(BUSINESS WIRE)--Cyclica, the partner of choice for data-driven drug discovery, and the Structural Genomics Consortium (SGC), a global public-private partnership dedicated to open science, ...

WALTHAM, Mass.; Sept. 28, 2023 (Business Wire) – X-Chem, a global leader in innovative drug discovery services, and the Structural Genomics Consortium (SGC), a public-private partnership dedicated to ...

SAN DIEGO--(BUSINESS WIRE)--Arima Genomics, Inc., the leader in 3D genomics, today announced the launch of new solutions for structural variant detection and gene regulation analysis. These solutions ...

In the last five years, researchers have published reports on the nucleotide sequences of several eukaryotic genomes. However, the functions of the majority of gene products from these genomes, ...

Arima Genomics, Inc., the leader in 3D genomics, has announced that new data on the detection of actionable structural variants from cancer samples embedded in formalin-fixed, paraffin-embedded (FFPE) ...

Structural biology is a field of science that uses a variety of techniques to determine the 3D structures of biomolecules such as proteins, nucleic acids and their complexes. These techniques allow ...

A team of Vanderbilt researchers has developed a novel tool in the detection and analysis of structural variants (SVs) in human genomes that could potentially transform genomic analysis and precision ...

An error in a gene, a mutation, can cause a disease, but the relationship between the genome of an organism and its physical characteristics, and exactly how genetic ...

Science, founded by Thomas A. Edison in 1880 and published by AAAS, today ranks as the world's largest circulation general science journal. Published 51 times a year, Science is renowned for its ...

PNAS is the world's most-cited multidisciplinary scientific serial. It publishes high-impact research reports, commentaries, perspectives, reviews, colloquium papers, and actions of the Academy. In ...