Department of Chemical and Process Engineering, University of Strathclyde, James Weir Building, 75 Montrose Street, Glasgow G1 1XJ, U.K. Department of Chemical and Process Engineering, University of ...
Laboratory of Materials Processing and Powder Metallurgy, Helsinki University of Technology, P.O. Box 6200, FIN-02015 HUT, Espoo, Finland, and Laboratory of Physical Chemistry and Electrochemistry, ...
Thermodynamic functions, Gibbs energy, enthalpy and entropy for the solution processes of ibuprofen (IBP) in acetone and dichloromethane (DCM) were calculated from solubility values obtained at ...
BASF and top universities jointly develop new process improving the bioavailability of active ingredients. The Supersonic spray-drying process yields stable and soluble amorphous nanoparticles. In ...
Industry is adapting to the increasing complexity and poor solubility and bioavailability of molecules in the pipeline. Poor solubility and low bioavailability have hindered the development pipeline ...
High-concentration injectable formulations present unique challenges. Poor solubility issues are often associated with small-molecule APIs formulated for oral administration. Solubility is also ...
On the other hand, it is well known that injectable homogeneous liquid formulations supply high doses of drug in small volumes, and thus, the solubility of drugs and other formulation components is ...
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