Initially, cells are dissociated from liver tissues into single-cell suspensions using in vivo enzymatic perfusion or ex vivo digestion methods. The cells of interest are then enriched from the ...

Immune low-response states significantly impact the effectiveness of immunotherapy in cancer treatment. These states ...

Advances in next-generation sequencing (NGS) technologies have lowered costs and reduced the complexity of DNA and RNA sequencing, enabling new possibilities when studying gene activity. In ...

Scaling up single-cell sequencing studies allows scientists to uncover rare cell types, better understand disease states, and track cellular changes over time. However, processing, assaying, and ...

This article explores how single-cell multiomics and spatial transcriptomics are illuminating early pregnancy, uncovering ...

A comprehensive review article titled “Bioinformatics perspectives on transcriptomics: A comprehensive review of bulk and single-cell RNA sequencing analyses,” published in Quantitative Biology, ...

Spatial transcriptomics (ST) technologies reveal the spatial organization of gene expression in tissues, providing critical insights into ...

Delaram Pouyabahar is a Canadian based computational biologist whose planned postdoctoral move to Harvard University ...

By recreating a fetal liver niche, FLOs show how liver and immune cells co-develop. Learn more about new groundbreaking ...

Kimchi may do far more than add flavor to meals—it could help fine-tune the human immune system. A clinical study using ...