The selection of suitable outcomes and sample size calculation are critical factors in the design of a randomised controlled trial (RCT). The goal of this study was to identify the range of outcomes ...

Background: Evidence from earlier studies indicates that intake of very long-chain n-3 polyunsaturated fatty acids (n-3 PUFA, also named omega-3 fatty acids) as present in fish oil reduces the risk of ...

Introduction Type 1 diabetes is characterised by progressive loss of pancreatic beta cells. Studies have shown that interleukin (IL)−17 is likely a mediator for this destruction. Whether inhibition of ...

The 2019 Nobel Prize in Economic Sciences was awarded to three economists on Monday for their pioneering research into the use of experimental approaches to fight global poverty. The trio, based in ...

Pragmatic Randomised Controlled Trial (RCTs) are the ‘gold standard’ test for evaluating whether a new intervention is better than an existing one and are routinely used in both real-world healthcare ...

Objective Anxiety affects up to one-third of adults with asthma and is linked to poorer disease outcomes and reduced quality ...

Background Injury risk in youth rugby has received much attention, highlighting the importance of establishing evidence-based injury reduction strategies. Aim To determine the efficacy of a movement ...

Preimplantation genetic testing for aneuploidies does not improve live birth rates in couples undergoing intracytoplasmic ...

A cluster randomised trial (CRT) is a randomised controlled trial in which pre-existing groups, called clusters, of individuals are randomly allocated to treatment arms. For example, clusters may be ...

Data sources Electronic databases: AMED, CINAHL, Cochrane Central Register of Controlled Trials, Embase, MEDLINE, Physiotherapy Evidence Database, PsycINFO, Scopus and SPORTDiscus. Eligibility ...

Elaine Mary Pascoe receives funding from the NHMRC. Laurent Billot receives project grant funding from the NHMRC Sabine Braat receives funding from NHMRC. University of Melbourne provides funding as a ...