Beyond platelets function in hemostasis, there is emerging evidence to suggest that platelets contribute crucially to inflammation and immune responses. Therefore, considering the detrimental role of ...

Cryopreserved platelets cost more and are linked to worse bleeding and clinical outcomes than liquid-stored platelets in a ...

Besides mediating hemostatic functions, platelets are increasingly recognized as important players of inflammation. Data from experiments in mice and men revealed various intersection points between ...

Figure 1: α-Granule proteins are concentrated on the surface of COAT-platelets. Dual stimulation of platelets with ionophore A23187 plus thrombin generated more than 95% COAT-platelets (Fig. 1i), ...

This review examines the evidence that platelets play a major role in localizing and controlling the burst of thrombin generation leading to fibrin clot formation. From the first functional ...

The use of cryopreserved platelets is associated with higher perioperative blood loss, higher transfusion use, and longer ICU ...

Manfredi et al1 explore the relationship between tumour necrosis factor α (TNFα), TNFα inhibition and platelet activation in rheumatoid arthritis (RA). Using elegant systems they demonstrate that TNFα ...

Platelets are blood components traditionally believed to have fundamental roles in vascular hemostasis and thrombosis. In recent years, platelets have received new attention for their roles in ...

The study included 202 adults undergoing cardiac surgery at 11 Australian tertiary hospitals between August 2021 and April ...