Continuous twin-screw granulation offers several options for increasing production scale. Thermo Fisher Scientific explains factors to consider in scale-up projects for manufacturing oral solid-dosage ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Control of powder properties is crucial for industrial processes across the food, ...

Wet granulation, dry granulation and direct blending are the most popular granulation processes for solid dosage form manufacture in the pharmaceutical industry, but they each have distinct drawbacks.

In dry granulation, powders bind because of the application of mechanical stress. As particles are forced to be within closer proximity, entrained air is forced out, bulk density increases, and a ...

Granulation processes are used for converting light fine powders into large, dense granules to make fast-dissolving drinks, optimized blends for compression tableting, and granules for waste water ...

Pharmaceutical manufacturing practices are advancing towards a future in which continuous manufacturing processes will be the norm. Developing and applying such techniques is therefore an essential ...