The brain regulates physiological functions integral to survival. However, the insight into brain neuronal regulation of peripheral immune function and the neuromediator systems and pathways involved ...

The basal forebrain degenerates in Alzheimer’s disease (AD) and this process is believed to contribute to the cognitive decline observed in AD patients. Impairment in spatial navigation is an early ...

Striatal dysfunction plays an important role in dystonia, but the striatal cell types that contribute to abnormal movements are poorly defined. We demonstrate that conditional deletion of the DYT1 ...

Zhao et al. report valuable adverse effects on cell proliferation, differentiation and gene expression, possibly linked to reduced binding activity of the transcription factor GTF2IRD1 to the ...

Summary: Brain in a dish research helps researchers identify defective cell migration caused by autism related disorders. Source: NIH/NIMH. Autism-related errant migration of neurons corrected in ...

A group of researchers at University of California San Diego School of Medicine led an investigation that offers new insight into the development of the human forebrain. The study, led by Changuk ...

Summary: Researchers discovered that anxious individuals utilize a less optimal region of the forebrain when navigating socially challenging situations compared to their non-anxious counterparts. This ...