SPECT of striatal dopamine transporter (DAT) availability with N-ω-fluoropropyl-2β-carbomethoxy-3β-(4-123 I-iodophenyl)nortropane ([123 I]FP-CIT) is widely used to support the diagnostic work-up in ...
Objectives to determine if DAT and D2 receptor SPECT can distinguish between vascular parkinsonism (VP) and idiopathic parkinsonian syndrome (IPS) Methods Included were 15 consecutive pat. with ...
Background: Dopamine transporter single-photon emission computed tomography (DAT-SPECT) is a crucial tool for evaluating patients with Parkinson’s disease (PD). However, its implication is limited by ...
Degeneration of dopaminergic neurons is a hallmark of Parkinson’s disease. However, its link to Parkinson’s disease symptoms remains unclear. Striatal resting state functional connectivity ...
Abstract: Dopamine transporter (DAT) SPECT imaging is widely used for the diagnosis of Parkinson's disease (PD). Investigations on quantitative analysis of DAT images have been performed using ...
Pterin species participate in dopamine biosynthesis, and abnormal pteridine metabolism contributes to reduced dopamine. GTP cyclohydrolase 1 (GCH-1) deficiency, which triggers pteridine hypometabolism ...
Abstract: Dopamine transporter (DAT) SPECT is a competent diagnostic tool for Parkinson’s disease (PD). However, image degradation factors like attenuation, scatter and penetration affect its image ...
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