Gprotein-coupled receptors (GPCRs) are an important class of receptor in modern drug discovery. This superfamily of receptors is highly tractable for drug discovery purposes because many of these ...

The Transcreener ADP 2 Assay uses a highly selective antibody and far-red fluorescent tracer to directly detect ADP produced by any ADP-producing enzyme (i.e. kinases, ATPases, helicases, carboxylases ...

Cyclic GMP-AMP synthase (cGAS) functions as a foreign DNA sensor, triggering an immune response to pathogens by activating the STING (stimulator of interferon genes) receptor. Shortly after its ...