Cell line development (CLD) follows a process that has only changed slightly since it was established in the early days of biopharmaceutical development. The steps to create a stable, manufacturing ...

If modern cell-based bioprocessing is to improve its ability to churn out biotherapeutics—not just tried-and-true antibodies, but also bi- and trispecific antibodies, as well as viral antigens and ...

To achieve this progress, biologic production has had to reinvent itself. Although biologics were once sourced directly from donated blood plasma or cells, the backbone of this process is now a ...

Single-cell proteomics provides information about a cell at its protein level, which can prove useful for anticancer drug resistance and cell differentiation research. However, current proteomics ...

Successfully producing large quantities of biotherapeutics, including monoclonal antibodies and recombinant protein products, depends on robust and reliable cell line development (CLD). Issues that ...

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The Scientist spoke with Westermark about his team’s latest analysis of U87MG, which was published in Science Translational Medicine today (August 31). The Scientist: What led you to question the ...

A unique tool for the study of human glomerular disease. It is known and used worldwide by leading research groups and many of the world’s largest pharmaceutical companies. This conditionally ...