Highly expressed genes are encoded by codons that correspond to abundant tRNAs, a phenomenon thought to ensure high expression levels. An alternative interpretation is that highly expressed genes are ...

It has been observed for several proteins that slowing down the rate at which individual codons are translated can increase their probability of cotranslational protein folding, while speeding up ...

The manuscript explores the ways in which the genetic code evolves, specifically how stop codons are reassigned to become sense codons. The authors present phylogenetic data showing that mutations at ...

ヒト細胞のコドン（遺伝暗号）に隠された暗号を解明 －ヒトコドン最適化制御による治療戦略の開発へ－ 竹内理 医学研究科教授らの研究グループは、ヒト細胞において、遺伝暗号であるコドンの偏りが、メッセンジャーRNA（mRNA）の安定性を制御し ...

Department of Physical Biochemistry, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany Protein homeostasis of bacterial cells is maintained by coordinated processes of protein ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Embryogenesis entails dramatic shifts in mRNA ...

DNA has often been called “the book of life,” but this popular phrase makes some biologists squirm a bit. True, DNA bears our genes, which spell out the instructions our cells use to make ...

A new study finds that at least one Archaea has surprisingly flexibility when interpreting genetic code, which goes against a ...