Non-coding DNA variants contribute to acute lymphoblastic leukemia (ALL) chemotherapy resistance. St. Jude Children's Research Hospital scientists have identified specific DNA variants in the ...

Researchers have revealed that so-called “junk DNA” contains powerful switches that help control brain cells linked to ...

St. Jude Children’s Research Hospital scientists have identified specific DNA variants in the non-coding regions of the genome contributing to chemotherapy resistance in acute lymphoblastic leukemia ...

The accumulation of mutations in DNA is often mentioned as an explanation for the ageing process, but it remains just one hypothesis among many. A team from the University of Geneva (UNIGE), in ...

(L to R) Co-first author Jackson Mobley, PhD, corresponding author Daniel Savic, PhD, and co-first author Kashi Raj Bhattarai, PhD, all of the St. Jude Department of Pharmacy and Pharmaceutical ...

多くの配列バリアントがヒトの複雑な形質や疾患と関連付けられてきたが、それらの大半はノンコーディングDNA上にあるために、その生物学的機能の解明はいまだに困難である。今回我々は、SNP-SELEX（single-nucleotide polymorphism evaluation by systematic evolution of ligands ...

The study shows that a long non-coding RNA called CISTR-ACT acts as a master regulator of cell size, influencing how large or ...

The non-coding genome, once dismissed as "junk DNA", is now recognized as a fundamental regulator of gene expression and a key player in understanding complex diseases. Following the landmark ...

理化学研究所（理研）生命医科学研究センター統合ゲノミクス研究チームの矢崎潤史上級研究員、小原收チームリーダー、理研生命機能科学研究センター 細胞システム動態予測研究チームの城口克之チームリーダー、慶應義塾大学医学部の天谷雅行教授らの ...

DNA coding theory bridges the disciplines of mathematics, computer science and molecular biology by applying advanced algebraic and combinatorial techniques to the design of nucleotide sequences. This ...

龍谷大学生物多様性科学研究センターの伊藤玄客員研究員らの研究グループは、産学連携の共同研究を中央復建コンサルタンツと実施。自然再生プロジェクトの効果を評価するため、より現実的な生物種構成（ターゲットイメージ）の目標設定に関して ...