The energy landscape perspective is outlined with particular reference to biomolecules that perform multiple functions. We associate these multifunctional molecules with multifunnel energy landscapes, ...

To observe biomolecules at work they must reside in their native environments. For soluble proteins this is a physiological buffer. Membrane proteins, in addition, need to be embedded in a lipid ...

Oceans include the greatest extremes of pressure, temperature and light, and habitats can range from tropical waters to ocean trenches, several kilometers below sea level at high pressure. With its 70 ...