As more complex calculation and check inside ISR are introduced from v1.2.0, there is possibly some crash depending on use-case. You can modify to use larger HW_TIMER_INTERVAL_US, (from current 33.3uS ...
With some Arduino IDE versions, such as v1.8.19, upload directly via USB to some boards, such as Curiosity_AVR128DA48 or Curiosity_AVR128DB48 can't be done without ...