The interactions of cancer cells with components of the complement system are highly complex, leading to an outcome that is either favorable or detrimental to cancer cells. Currently, we perceive only ...

The classical pathway is activated by C1q-mediated recognition of the target. Further activation of this pathway causes C4b and its cleavage product iC4b to accumulate in the tissues. C4b binds to C2 ...

7 KU Leuven, Skeletal Biology and Engineering Research Centre, Department of Development and Regeneration, Leuven, Belgium 8 KU Leuven, Skeletal Biology and Engineering Research Centre, Department of ...